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The author or concept searched is found in the following 1 entries.
| Disputed term/author/ism | Author |
Entry |
Reference |
|---|---|---|---|
| Molecular Genetic Studies | Behavioral Genetics | Corr I 292 Molecular Genetic Studies/personality traits/behavioral genetics/Munafò: Problems with twin studies/VsTwin studies: Twin studies do not readily allow an estimation of gene × environment interaction effects, and these are typically included in the non-shared environment term, which also includes measurement error and other unmeasured effects such as developmental accidents due to chance. For these reasons, as genotyping of specific loci has become more cost-effective, research has moved towards the molecular genetic investigation of the biological basis of personality. >Personality traits, >Personality. Molecular genetic studies: a substantial literature has developed reporting data on the role of a variety of genetic variants, although only modest progress has been made in identifying molecular loci which robustly demonstrate association (Munafò, Clark, Moore et al. 2003)(1). Problems with molecular genetic studies/VsMolecular genetic studies: In common with genetic association studies in other disciplines, reports of highly significant associations between candidate genes and personality traits have typically not been followed by convincing replications. For instance, the report by Lesch’s group in 1996 (Lesch, Bengel, Heils et al. 1996)(2) of an association between variation in the promoter region of the serotonin transporter gene and emotional stability (or Neuroticism) generated much interest, but subsequent work has delivered inconsistent conclusions (Munafò, Clark and Flint 2005(3); Munafò, Clark, Moore et al. 2003(1); Schinka, Busch and Robichaux-Keene 2004(4); Sen, Burmeister and Ghosh 2004(5)). 1. Munafò, M. R., Clark, T. G., Moore, L. R., Payne, E., Walton, R. and Flint, J. 2003. Genetic polymorphisms and personality in healthy adults: a systematic review and meta-analysis, Molecular Psychiatry 8: 471–84 2. Lesch, K. P., Bengel, D., Heils, A., Sabol, S. Z., Greenberg, B. D., Petri, S. et al. 1996. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region, Science 274: 1527–31 3. Munafò, M. R., Clark, T. G. and Flint, J. 2005. Does measurement instrument moderate the association between the serotonin transporter gene and anxiety-related personality traits? A meta-analysis, Molecular Psychiatry 10: 415–19 4. Schinka, J. A., Busch, R. M. and Robichaux-Keene, N. 2004. A meta-analysis of the association between the serotonin transporter gene polymorphism (5-HTTLPR) and trait anxiety, Molecular Psychiatry 9: 197–202 5. Sen, S., Burmeister, M. and Ghosh, D. 2004. Meta-analysis of the association between a serotonin transporter promoter polymorphism (5-HTTLPR) and anxiety-related personality traits, American Journal of Medical Genetics B Neuropsychiatric Genetics 127: 85–9 Marcus R. Munafò,“Behavioural genetics: from variance to DNA“, in: Corr, Ph. J. & Matthews, G. (eds.)2009. The Cambridge handbook of Personality Psychology. New York: Cambridge University Press |
Corr I Philip J. Corr Gerald Matthews The Cambridge Handbook of Personality Psychology New York 2009 Corr II Philip J. Corr (Ed.) Personality and Individual Differences - Revisiting the classical studies Singapore, Washington DC, Melbourne 2018 |
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